NOMO-1（人白血病細(xì)胞）

CBP60515

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產(chǎn)品描述

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I. General information
Synonyms:	NOMO-1
Background:	established from the bone marrow of a 31-year-old woman with acute myeloid leukemia (AML FAB M5a) at 2nd relapse; described in the literature to show strong lysozyme activity in the cytoplasm, phagocytic activities, and cells are responsive to induction of differentiation with TPA; cells carry the t(9;11)(q23;p22) KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) alteration
Species:	human (Homo sapiens)
Tissue:	N/A
Disease:	acute myeloid leukemia
Gender:	N/A
Morphology:	single round cells growing in suspension;
Growth Mode:	N/A
Doubling Time:	ca. 35 hours
DNA Profile:	N/A Our Cell Line Authentication Service
Culture Medium:	RPMI1640+10%FBS NOMO-1完全培養(yǎng)基，# CBP60515M We strongly suggest to purchase the complete medium from us.
Cryopreservation medium:	90%FBS+10%DMSO
Mycoplasma:	negative in microbiological culture, PCR assays
Immunology:	CD3 -, CD4 +, CD13 +, CD14 -, CD15 +, CD19 -, CD33 +, CD34 -, HLA-DR +; image
Fingerprint:	multiplex PCR of minisatellite markers revealed a unique DNA profile
Species:	confirmed as human by cytogenetics
Cytogenetics:	human hyperdiploid karyotype with 8% polyploidy - 46-47<2n>XX, +8, -13, +mar, add(7)(q32), der(9)del(9)(p11p13-21)t(9;11)(p22;q23), t(9;13)(q13;q11), der(11)t(9;11)(p22;q23) - carries reciprocal t(9;11) with rearrangement of KMT2A (MLL) - matches published karyotype
Molec. Genetics:	expression of fusion gene KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) confirmed by RT-PCR
Virus	PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/II -, MLV -, SMRV -
Comments:	For more information, please contact us (4008-750-250).

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理：18240630236/15715191010 華中&華西銷售經(jīng)理：18071545918 華中&西南銷售經(jīng)理：13871580511 華北銷售經(jīng)理：18628311252 全國銷售經(jīng)理：13816461235
診斷標(biāo)準(zhǔn)品聯(lián)系方式：華東銷售經(jīng)理：15000320447 華北銷售經(jīng)理：18628311252 華中&華西銷售經(jīng)理：18071545918 華中&西南銷售經(jīng)理：13871580511 全國銷售經(jīng)理：13816461235

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